INT249143

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Was) protein complex assembly (Was) cytoplasm (Was)
Anatomy Link Frequency
thymocytes 1
Was (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 28 60.36 Quite High
Wiskott-aldrich Syndrome 54 51.84 Quite High
Immunodeficiency 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Eczema 4 5.00 Very Low Very Low Very Low
Thrombocytopenia 4 5.00 Very Low Very Low Very Low
Hemorrhage 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Uveitis 2 5.00 Very Low Very Low Very Low
Immune System Diseases 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that for WASP mutations resulting in no protein expression at all, N-WASP partially compensates for lack of WASP in supporting the DN3 to DP transition, but that WASP?
WASP Neg (lack) Binding (lack) of
1) Confidence 0.32 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2567846 Disease Relevance 0 Pain Relevance 0
Based on the finding of multiple somatic mutations, the known maturation pathway for T-lineage cells and the known defects of T cells and precursor thymocytes in mice with truncated WASP, we hypothesize that the presence of truncated WASP (WASP?
WASP Binding (presence) of in thymocytes
2) Confidence 0.30 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2567846 Disease Relevance 0.16 Pain Relevance 0

General Comments

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