INT249248

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Context Info
Confidence 0.60
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.05
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYBB) oxidoreductase activity (CYBB) plasma membrane (CYBB)
cytoplasm (CYBB)
Anatomy Link Frequency
leukocyte 1
neutrophils 1
CYBB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 42 86.64 High High
rheumatoid arthritis 4 75.44 Quite High
Osteoarthritis 4 74.48 Quite High
cINOD 9 68.96 Quite High
Arthritis 6 61.36 Quite High
Inflammatory mediators 1 58.72 Quite High
Pain 2 11.20 Low Low
ischemia 20 5.00 Very Low Very Low Very Low
cva 14 5.00 Very Low Very Low Very Low
addiction 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 49 86.64 High High
Stress 22 83.44 Quite High
Rheumatoid Arthritis 4 75.44 Quite High
Osteoarthritis 4 74.48 Quite High
Disease 31 73.68 Quite High
Arthritis 6 61.36 Quite High
Edema 10 58.00 Quite High
Hypersensitivity 2 42.16 Quite Low
Asthma 11 31.60 Quite Low
Neutrophil Disorders 4 15.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
involved the inhibition of the NADPH-oxidase-dependent superoxide production,
Neg (inhibition) Transcription (inhibition) of NADPH-oxidase
1) Confidence 0.60 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.84 Pain Relevance 0.46
since sulfhydryl groups are important for the function of the leukocyte NADPH-oxidase, the oxidant effect of apocynin could
Transcription (function) of leukocyte NADPH-oxidase in leukocyte
2) Confidence 0.52 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.15 Pain Relevance 0
NADPH oxidase was first described in neutrophils, where it is normally inactive.
Transcription (described) of NADPH oxidase in neutrophils
3) Confidence 0.44 Published 2008 Journal J Leukoc Biol Section Body Doc Link PMC2567897 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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