INT249265

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.12
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NCF1) cytosol (NCF1) GTPase activity (NCF1)
cytoplasm (NCF1)
Anatomy Link Frequency
plasma 1
monocytes 1
leukocytes 1
NCF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 8 74.72 Quite High
ischemia 30 49.00 Quite Low
Inflammation 67 48.80 Quite Low
antagonist 4 37.12 Quite Low
addiction 9 33.04 Quite Low
cva 21 5.00 Very Low Very Low Very Low
cINOD 14 5.00 Very Low Very Low Very Low
Arthritis 9 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 16 87.48 High High
Urological Neuroanatomy 27 84.56 Quite High
Cancer 12 78.36 Quite High
Targeted Disruption 6 78.20 Quite High
Breast Cancer 3 56.04 Quite High
Lung Injury 12 49.96 Quite Low
Cv Unclassified Under Development 27 49.00 Quite Low
INFLAMMATION 79 48.80 Quite Low
Disease 49 47.76 Quite Low
Prostate Cancer 2 18.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
antisense inhibits phosphorylation and translocation of p47phox induced by fMLF, providing evidence for the involvement of PKC?
Localization (translocation) of p47phox
1) Confidence 0.21 Published 2008 Journal J Leukoc Biol Section Body Doc Link PMC2567897 Disease Relevance 0.08 Pain Relevance 0.07
Apocynin prevents the translocation of p47phox to Nox2 in leukocytes, monocytes,
Localization (translocation) of p47phox in leukocytes
2) Confidence 0.16 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.35 Pain Relevance 0
the translocation of p47-phox and p67-phox though it does not mediate it
Localization (translocation) of p47-phox
3) Confidence 0.16 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.35 Pain Relevance 0
Thus, S100 protein translocation to the plasma membrane together with p67phox, p47phox, and Rac supports the hypothesis that these proteins might deliver bound arachidonic acid in a Ca2+-dependent manner to the NADPH oxidase [157].


Localization (translocation) of p47phox in plasma
4) Confidence 0.09 Published 2008 Journal J Leukoc Biol Section Body Doc Link PMC2567897 Disease Relevance 0 Pain Relevance 0
Apocynin prevents the translocation of p47phox to Nox2 in leukocytes, monocytes,
Localization (translocation) of p47phox in monocytes
5) Confidence 0.05 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 0.35 Pain Relevance 0

General Comments

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