INT249273

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.26
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CA2) extracellular space (CA2) lyase activity (CA2)
response to stress (CA2) cytoplasm (CA2)
Anatomy Link Frequency
cardiomyocytes 2
CA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 6 93.68 High High
Action potential 40 93.04 High High
action potential duration 20 83.80 Quite High
antagonist 4 34.88 Quite Low
lidocaine 9 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
TRP channel 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 5 98.40 Very High Very High Very High
Targeted Disruption 6 77.52 Quite High
Cardiovascular Disorder Under Development 4 50.00 Quite Low
Prostate Cancer 12 44.36 Quite Low
Apoptosis 9 29.08 Quite Low
Stress 6 28.36 Quite Low
Colon Cancer 1 19.64 Low Low
Cancer 13 5.00 Very Low Very Low Very Low
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Arrhythmia Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
REGULATION OF Ca2+ INFLUX BY ACTIVATION OF THE NADPH OXIDASE
Regulation (REGULATION) of Regulation (REGULATION) of Ca2
1) Confidence 0.23 Published 2008 Journal J Leukoc Biol Section Body Doc Link PMC2567897 Disease Relevance 0.08 Pain Relevance 0
Interestingly all four candidates identified were previously shown to be involved in Ca2+ signaling and the regulation of intracellular Ca2+ concentrations during cell growth and death.
Regulation (involved) of Regulation (regulation) of Ca2 associated with death
2) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2935366 Disease Relevance 0.19 Pain Relevance 0
Furthermore, intracellular Ca2+ and Na+ levels are very sensitive to INaK and INaCa, which supports our results obtained in virtual human cardiomyocytes.
Regulation (sensitive) of Regulation (intracellular) of Ca2 in cardiomyocytes
3) Confidence 0.03 Published 2010 Journal Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Section Body Doc Link PMC2944395 Disease Relevance 0 Pain Relevance 0.31

General Comments

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