INT249316

Context Info Confidence 0.36 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.11 Pain Relevance 0.12

transport (Preb) vesicle-mediated transport (Preb) endoplasmic reticulum (Preb) nucleus (Preb) DNA binding (Preb)

Anatomy Link Frequency neurons 2 Preb (Mus musculus)

Pain Link Frequency Relevance Heat Neuronal excitability 5 77.28 gABA 6 62.88 depression 17 55.68 adenocard 11 52.48 Glutamate 1 49.12 Serotonin 1 47.44 medulla 14 36.32 Spinal cord 6 35.52 antagonist 8 5.00 agonist 5 5.00

Disease Link Frequency Relevance Heat Depression 18 55.68 Hypoxia 5 55.24 Stress 2 25.16 Convulsion 6 5.00 Rheumatoid Arthritis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

However, A1R activation clearly decreases excitability of preBötC neurons, an effect that alone can decrease transmitter release.

Negative_regulation (decreases) of preB Binding (excitability) of in neurons

1) Confidence 0.36 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567986 Disease Relevance 0.11 Pain Relevance 0.12

General Comments

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