INT249317

Context Info Confidence 0.39 First Reported 2008 Last Reported 2008 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0.08

transport (Preb) vesicle-mediated transport (Preb) endoplasmic reticulum (Preb) nucleus (Preb) DNA binding (Preb)

Anatomy Link Frequency patterning 2 Preb (Mus musculus)

Pain Link Frequency Relevance Heat depression 17 100.00 adenocard 11 50.00 medulla 14 5.00 antagonist 8 5.00 Spinal cord 6 5.00 gABA 6 5.00 Neuronal excitability 5 5.00 agonist 5 5.00 Action potential 2 5.00 tetrodotoxin 1 5.00

Disease Link Frequency Relevance Heat Depression 18 100.00 Convulsion 6 5.00 Hypoxia 5 5.00 Rheumatoid Arthritis 3 5.00 Stress 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although GABAAergic and glycinergic transmission affect the patterning and excitability of the respiratory network within in vitro preparations from neonatal mammals, the data presented herein show that the depression of preBötC rhythmogenesis by A1R activation is unaffected by reducing the overall level of synaptic input received by preBötC neurons, or by antagonizing GABAA or GABAA and glycine receptors.

Neg (unaffected) Regulation (unaffected) of Negative_regulation (depression) of preB in patterning associated with depression

1) Confidence 0.39 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2567986 Disease Relevance 0.16 Pain Relevance 0.08

General Comments

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