INT249514

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ephb3)
Anatomy Link Frequency
fibroblasts 1
Ephb3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 30 99.36 Very High Very High Very High
Dorsal horn neuron 6 97.64 Very High Very High Very High
Hyperalgesia 11 80.68 Quite High
nMDA receptor 28 61.68 Quite High
B1 receptor 1 61.12 Quite High
intrathecal 16 59.28 Quite High
Dorsal horn 11 56.28 Quite High
Inflammation 9 50.00 Quite Low
Eae 10 46.08 Quite Low
Neuropathic pain 9 44.32 Quite Low
Disease Link Frequency Relevance Heat
Frailty 1 95.68 Very High Very High Very High
Hyperalgesia 25 80.68 Quite High
INFLAMMATION 9 50.00 Quite Low
Nociception 14 46.24 Quite Low
Inflammatory Pain 7 46.08 Quite Low
Neuropathic Pain 18 44.32 Quite Low
Pain 13 5.00 Very Low Very Low Very Low
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Eph-B1 is present in the adult spinal cord dorsal horn neurons (Battaglia et al., 2003), Eph-B2 is found in meningeal fibroblasts of the spinal cord (Bundesen et al., 2003), while Eph-B3 is found in low amount in normal animals, but is upregulated in white matter astrocytes and motoneurons following a spinal cord injury (Miranda et al., 1999).
Localization (found) of Eph-B3 in fibroblasts associated with dorsal horn neuron and spinal cord
1) Confidence 0.15 Published 2008 Journal Neuroscience Section Body Doc Link PMC2568875 Disease Relevance 0.26 Pain Relevance 0.51

General Comments

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