INT249516

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Fyn) endosome (Fyn) mitochondrion (Fyn)
plasma membrane (Fyn)
Fyn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 28 95.96 Very High Very High Very High
Glutamate 3 95.96 Very High Very High Very High
Spinal cord 30 72.28 Quite High
Eae 10 71.60 Quite High
Hippocampus 5 68.16 Quite High
Inflammation 9 50.00 Quite Low
Thermal hyperalgesia 13 36.88 Quite Low
intrathecal 16 32.28 Quite Low
Neuropathic pain 9 10.28 Low Low
Hyperalgesia 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 77.80 Quite High
Targeted Disruption 2 76.32 Quite High
Inflammatory Pain 7 71.60 Quite High
INFLAMMATION 9 50.00 Quite Low
Hyperalgesia 25 36.88 Quite Low
Neuropathic Pain 18 10.28 Low Low
Nociception 14 5.00 Very Low Very Low Very Low
Pain 13 5.00 Very Low Very Low Very Low
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They also showed that in HEK293T cells mutation of the Src-binding site on EphB2 or expression of a dominant negative of Fyn (inhibiting Src family kinases) disabled the phosphorylation of NR2B effect of ephrinB2 and the potentiation of NMDA receptor activity.
Negative_regulation (inhibiting) of Gene_expression (expression) of Fyn associated with nmda receptor
1) Confidence 0.18 Published 2008 Journal Neuroscience Section Body Doc Link PMC2568875 Disease Relevance 0.23 Pain Relevance 0.32

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox