INT249536

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (EPHA1, Efnb2) plasma membrane (EPHA1, Efnb2)
Anatomy Link Frequency
spinal cord 1
EPHA1 (Homo sapiens)
Efnb2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 30 99.24 Very High Very High Very High
Pain 6 97.84 Very High Very High Very High
nMDA receptor 28 96.40 Very High Very High Very High
Glutamate receptor 2 90.96 High High
intrathecal 16 70.40 Quite High
Hyperalgesia 11 67.16 Quite High
Glutamate 3 61.00 Quite High
Eae 10 50.88 Quite High
Inflammation 9 50.00 Quite Low
Lasting pain 7 49.76 Quite Low
Disease Link Frequency Relevance Heat
Pain 13 97.84 Very High Very High Very High
Hyperalgesia 25 67.16 Quite High
Nociception 14 65.64 Quite High
Inflammatory Pain 7 50.88 Quite High
INFLAMMATION 9 50.00 Quite Low
Neuropathic Pain 18 17.68 Low Low
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Nervous System Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We previously identified a novel role for ephrinB2 and its Eph tyrosine kinase receptor(s) in vivo in the spinal cord, as neuromodulators of pain signaling, probably acting via NMDA receptors (Battaglia et al., 2003).
Eph Binding (receptor) of ephrinB2 in spinal cord associated with pain, nmda receptor and spinal cord
1) Confidence 0.02 Published 2008 Journal Neuroscience Section Body Doc Link PMC2568875 Disease Relevance 0.28 Pain Relevance 0.52

General Comments

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