INT249551

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.16
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GNAS) intracellular (GNAS) GTPase activity (GNAS)
transmembrane transport (GNAS) cytoplasm (GNAS) signal transducer activity (GNAS)
Anatomy Link Frequency
colon 3
putamen 3
caudate nucleus 1
muscle 1
GNAS (Homo sapiens)
Pain Link Frequency Relevance Heat
Thalamus 4 100.00 Very High Very High Very High
Substantia nigra 4 96.44 Very High Very High Very High
amygdala 12 92.56 High High
medulla 8 88.68 High High
Spinal cord 12 86.08 High High
Hippocampus 28 81.76 Quite High
cerebral cortex 12 5.00 Very Low Very Low Very Low
Nerve growth factor 8 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 4 82.40 Quite High
Cognitive Disorder 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Huntington's Chorea 4 5.00 Very Low Very Low Very Low
Nervous System Malformation 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BDNF expression was also very low in the globus pallidus, striatum (caudate nucleus and putamen), and thalamus, with the exception of exon IXabcd transcripts, which were expressed at relatively high levels in these regions.
Negative_regulation (low) of in caudate nucleus Neg (exception) Transcription (exception) of exon in putamen associated with thalamus
1) Confidence 0.06 Published 2007 Journal Genomics Section Body Doc Link PMC2568880 Disease Relevance 0.08 Pain Relevance 0.23
For example, antiBDNF transcripts with exon 10 were present in the colon and muscle, whereas transcripts with exon 9 were not expressed in these tissues.
Negative_regulation (present) of Transcription (transcripts) of exon in colon
2) Confidence 0.06 Published 2007 Journal Genomics Section Body Doc Link PMC2568880 Disease Relevance 0 Pain Relevance 0.07
BDNF expression was also very low in the globus pallidus, striatum (caudate nucleus and putamen), and thalamus, with the exception of exon IXabcd transcripts, which were expressed at relatively high levels in these regions.
Negative_regulation (low) of Neg (exception) Transcription (exception) of exon in putamen associated with thalamus
3) Confidence 0.02 Published 2007 Journal Genomics Section Body Doc Link PMC2568880 Disease Relevance 0.08 Pain Relevance 0.23
For example, antiBDNF transcripts with exon 10 were present in the colon and muscle, whereas transcripts with exon 9 were not expressed in these tissues.
Negative_regulation (present) of in muscle Transcription (transcripts) of exon in colon
4) Confidence 0.02 Published 2007 Journal Genomics Section Body Doc Link PMC2568880 Disease Relevance 0 Pain Relevance 0.07

General Comments

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