INT249566

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.82
Pain Relevance 3.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Psmd1) plasma membrane (Oprd1) cellular_component (Psmd1)
cytoplasm (Oprd1) signal transducer activity (Oprd1)
Anatomy Link Frequency
ACC 2
Oprd1 (Rattus norvegicus)
Psmd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 201 100.00 Very High Very High Very High
primary somatosensory cortex 168 100.00 Very High Very High Very High
opioid receptor 63 100.00 Very High Very High Very High
gABA 9 97.20 Very High Very High Very High
mu opioid receptor 3 95.16 Very High Very High Very High
Morphine 264 92.68 High High
Enkephalin 99 91.68 High High
antagonist 18 91.16 High High
Spinal cord 6 85.68 High High
Antinociceptive 27 75.00 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 285 98.48 Very High Very High Very High
Nociception 90 88.24 High High
Urological Neuroanatomy 3 42.16 Quite Low
Aggression 6 34.12 Quite Low
Anxiety Disorder 6 33.52 Quite Low
Hyperalgesia 12 32.64 Quite Low
Pain 33 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Percent increases in opioid receptor binding in S1 and ACC were 5.1% and 5.8%, respectively.


opioid receptor Binding (binding) of S1 in ACC associated with opioid receptor and anterior cingulate cortex
1) Confidence 0.01 Published 2008 Journal Mol Pain Section Abstract Doc Link PMC2569012 Disease Relevance 0.17 Pain Relevance 1.31
We found 5.8% and 5.1% increases in opioid receptor binding in the ACC and S1 respectively in the present study in KO mice compared to WT mice.
opioid receptor Binding (binding) of S1 associated with targeted disruption, primary somatosensory cortex, opioid receptor and anterior cingulate cortex
2) Confidence 0.01 Published 2008 Journal Mol Pain Section Body Doc Link PMC2569012 Disease Relevance 0.49 Pain Relevance 1.18
Percent increases in opioid receptor binding in S1 and ACC were 5.1% and 5.8%, respectively.


opioid receptor Binding (binding) of S1 in ACC associated with opioid receptor and anterior cingulate cortex
3) Confidence 0.01 Published 2008 Journal Mol Pain Section Abstract Doc Link PMC2569012 Disease Relevance 0.17 Pain Relevance 1.31

General Comments

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