INT249597

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Jak2, Stat1) nucleus (Jak2, Stat1) cell differentiation (Jak2)
histone binding (Jak2) enzyme binding (Stat1) DNA binding (Stat1)
Jak2 (Mus musculus)
Stat1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 53.08 Quite High
withdrawal 1 49.24 Quite Low
Nerve growth factor 2 48.04 Quite Low
Inflammation 19 45.20 Quite Low
Bioavailability 1 42.56 Quite Low
Inflammatory mediators 1 30.72 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 7 71.44 Quite High
Neurodegenerative Disease 8 56.92 Quite High
Injury 1 49.84 Quite Low
INFLAMMATION 22 45.20 Quite Low
Disease 9 33.16 Quite Low
Stress 1 16.16 Low Low
Death 4 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphatidylinositol 3-kinase (PI3K), its effector kinase Akt, JAK1, and JAK2 are all required for phosphorylation of both serine 727 and tyrosine 701 of STAT1 [62].
JAK2 Positive_regulation (required) of Phosphorylation (phosphorylation) of STAT1
1) Confidence 0.20 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2569027 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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