INT249601

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cd40) extracellular region (Cd40) plasma membrane (Cd40)
enzyme binding (Cd40)
IFNA1 (Homo sapiens)
Cd40 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 61.20 Quite High
Inflammation 19 56.24 Quite High
Nerve growth factor 2 26.32 Quite Low
withdrawal 1 23.20 Low Low
Central nervous system 6 14.96 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 7 95.08 Very High Very High Very High
INFLAMMATION 22 61.20 Quite High
Disease 9 55.20 Quite High
Neurodegenerative Disease 8 52.08 Quite High
Cancer 3 44.80 Quite Low
Injury 1 21.68 Low Low
Death 4 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it appears to be as necessary as serine 727 phosphorylation for STAT1 signaling as apigenin effectively reduces CD40 expression in the presence of IFN-?
IFN Negative_regulation (reduces) of Gene_expression (expression) of CD40
1) Confidence 0.42 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2569027 Disease Relevance 0.51 Pain Relevance 0.09

General Comments

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