INT249741

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
respiratory 1


Pain Term Frequency Confidence Heat
drug abuse 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Targeted Disruption 70 94.80 High High
Aging 15 84.04 Quite High
Hypertrophy 2 31.00 Quite Low
Lifespan 8 21.00 Low Low
Heart Rate Under Development 3 10.24 Low Low
Anaemia 1 5.00 Very Low Very Low Very Low
Parkinson's Disease 11 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Mitochondrial Myopathies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mitochondrial redox state was monitored at two levels of the respiratory chain, the cytochrome c oxidase and the free NADH/NAD+ pool.
Gene_expression (levels) of cytochrome c oxidase in respiratory
1) Confidence 0.65 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680037 Disease Relevance 0.54 Pain Relevance 0
Physical exercise increases the activity of some mitochondrial enzymes, like citrate synthase, cytochrome C oxidase and ?
Gene_expression (citrate synthase) of cytochrome C oxidase
2) Confidence 0.65 Published 2008 Journal Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine Section Body Doc Link PMC2990231 Disease Relevance 0 Pain Relevance 0
Using mass spectrometry methods, we demonstrated that numerous proteins involved in the citric acid cycle (isocitrate dehydrogenase, aspartate aminotransferase, malate dehydrogenase, and oxoglutarate dehydrogenase) and electron transport (cytochrome c oxidase, ubiquinol-cytochrome c reductase, NADH dehydrogenase, and ATP synthase) were expressed at lower levels in OS compared with YS subjects.
Gene_expression (expressed) of cytochrome c oxidase
3) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2570389 Disease Relevance 0.08 Pain Relevance 0

General Comments

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