INT249798

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Skp2)
Skp2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 63.60 Quite High
analgesia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 97.00 Very High Very High Very High
Injury 6 80.16 Quite High
Targeted Disruption 5 76.32 Quite High
Hyperplasia 2 73.52 Quite High
Impaired Glucose Tolerance 3 63.60 Quite High
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
Polyploidy 2 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several of FoxM1's direct transcriptional targets inhibit p27Kip1 by promoting its ubiquitination and subsequent degradation (Skp2, Cks1) (14) or its nuclear export (kinase-interacting stathmim) (30).
Positive_regulation (promoting) of Localization (export) of Skp2
1) Confidence 0.41 Published 2008 Journal Diabetes Section Body Doc Link PMC2570403 Disease Relevance 0.56 Pain Relevance 0.03

General Comments

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