INT249829

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (CHI3L1, AKT1) cytoplasm (CHI3L1, AKT1) cell differentiation (AKT1)
nucleoplasm (AKT1) transport (AKT1) protein modification process (AKT1)
Anatomy Link Frequency
fibroblast 1
CHI3L1 (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 14 79.76 Quite High
cytokine 2 63.92 Quite High
tolerance 9 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 3 95.92 Very High Very High Very High
Arthritis 1 94.92 High High
Disease 4 81.84 Quite High
INFLAMMATION 15 79.76 Quite High
Obesity 54 74.48 Quite High
Insulin Resistance 4 36.08 Quite Low
Diabetes Mellitus 22 25.84 Quite Low
Impaired Glucose Tolerance 9 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, YKL-40 is known to stimulate growth of fibroblast cells (11), activate the AKT and phosphoinositide-3 kinase signaling pathway, exert antiapoptosis (12), and function in angiogenesis (7) and may take part in the innate immune response (13).
YKL-40 Positive_regulation (activate) of AKT in fibroblast
1) Confidence 0.47 Published 2008 Journal Diabetes Section Body Doc Link PMC2570404 Disease Relevance 0.69 Pain Relevance 0.14

General Comments

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