INT249831

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.81
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CHI3L1, IL6) extracellular region (CHI3L1, IL6) aging (IL6)
endoplasmic reticulum (CHI3L1) proteinaceous extracellular matrix (CHI3L1) carbohydrate metabolic process (CHI3L1)
Anatomy Link Frequency
plasma 3
CHI3L1 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 27 86.08 High High
Inflammation 42 78.96 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 162 99.36 Very High Very High Very High
Infection 6 87.68 High High
Diabetes Mellitus 66 87.32 High High
Impaired Glucose Tolerance 27 86.08 High High
INFLAMMATION 45 78.96 Quite High
Disease 12 39.12 Quite Low
Insulin Resistance 12 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, we found a relationship between plasma IL-6 and plasma YKL-40 but no association between YKL-40 and markers of obesity.
YKL-40 Neg (no) Binding (association) of IL-6 in plasma associated with obesity
1) Confidence 0.30 Published 2008 Journal Diabetes Section Body Doc Link PMC2570404 Disease Relevance 0.82 Pain Relevance 0.06
However, as is evident from Table 2A, plasma IL-6 can only explain 3% of the variation in plasma YKL-40, indicating that other factors may be more important for the production/release of YKL-40.
plasma YKL-40 Binding (explain) of IL-6 in plasma
2) Confidence 0.21 Published 2008 Journal Diabetes Section Body Doc Link PMC2570404 Disease Relevance 1.02 Pain Relevance 0.07
or fasting plasma glucose, plasma YKL-40 was positively associated with fasting plasma glucose (P = 0.0014) and plasma IL-6 (P = 0.0303).
plasma YKL-40 Binding (associated) of IL-6 in plasma
3) Confidence 0.21 Published 2008 Journal Diabetes Section Body Doc Link PMC2570404 Disease Relevance 0.98 Pain Relevance 0.14

General Comments

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