INT249878

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpr17) plasma membrane (Gpr17) signal transducer activity (Gpr17)
Anatomy Link Frequency
brain 1
Gpr17 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 39 90.32 High High
ischemia 48 88.04 High High
Potency 3 46.16 Quite Low
antagonist 24 19.12 Low Low
cerebral cortex 6 8.60 Low Low
imagery 21 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
Multiple sclerosis 9 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 100.00 Very High Very High Very High
Immunization 3 90.16 High High
Cv Unclassified Under Development 33 88.04 High High
Death 36 86.08 High High
Stress 6 83.12 Quite High
Middle Cerebral Artery Infarction 87 80.32 Quite High
Brain Injury 27 60.00 Quite High
Anaplastic Astrocytoma 6 50.20 Quite High
Contagious Ecthyma 3 26.88 Quite Low
Brain Hemorrhage 24 16.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The in vivo knock down of GPR17 markedly attenuates brain ischemic damage in mice
GPR17 Binding (knock) of in brain associated with targeted disruption
1) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2570486 Disease Relevance 0.94 Pain Relevance 0.09
Interestingly, in some Olig2 or NG2-labeled cells, GPR17 immunoreactivity displayed an asymmetrical subcellular localization, suggesting GPR17 accumulation in the Golgi apparatus (Figure 2H?
GPR17 Binding (immunoreactivity) of
2) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2570486 Disease Relevance 0 Pain Relevance 0
S binding to purified membranes; see [13]), GPR17 activation in the heterologous system was determined by testing the increase of [35S]GTP?
GPR17 Binding (binding) of
3) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2570486 Disease Relevance 0.14 Pain Relevance 0.05

General Comments

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