INT249892

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cysltr1, Gpr17) plasma membrane (Cysltr1, Gpr17) signal transducer activity (Cysltr1, Gpr17)
Cysltr1 (Mus musculus)
Gpr17 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 8 88.96 High High
excitatory amino acid 1 88.24 High High
Inflammation 4 58.36 Quite High
ischemia 16 58.08 Quite High
Inflammatory response 1 52.76 Quite High
Multiple sclerosis 3 8.08 Low Low
agonist 13 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Injury 9 89.80 High High
Middle Cerebral Artery Infarction 29 83.88 Quite High
Injury 7 64.52 Quite High
Cerebral Hypoxia 1 64.08 Quite High
INFLAMMATION 5 58.36 Quite High
Cv Unclassified Under Development 11 58.08 Quite High
Stroke 1 55.04 Quite High
Disease 3 53.52 Quite High
Asthma 1 43.92 Quite Low
Demyelinating Disease 6 8.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have recently reported that GPR17, a previously orphan G protein-coupled receptor [10] (GPCR) at an intermediate phylogenetic position between P2Y and CysLT receptor families, is a new P2Y receptor specifically activated by both uracil nucleotides (UDP, UDP-glucose and UDP-galactose) and cysLTs (LTD4 and LTC4) [11].
LTD4 Positive_regulation (activated) of GPR17
1) Confidence 0.09 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2570486 Disease Relevance 0.92 Pain Relevance 0.20

General Comments

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