INT249913

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.82
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hif1a) signal transduction (Hif1a) nucleolus (Hif1a)
nucleus (Hif1a) protein binding transcription factor activity (Hif1a) DNA binding (Hif1a)
Hif1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 91.20 High High
ischemia 4 87.36 High High
Calcium channel 2 87.32 High High
nMDA receptor 9 50.00 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 204 99.40 Very High Very High Very High
Injury 1 90.72 High High
Cv Unclassified Under Development 2 87.36 High High
Apoptosis 4 59.96 Quite High
Retina Disease 2 25.28 Quite Low
Reperfusion Injury 1 23.92 Low Low
Stress 5 19.28 Low Low
Ganglion Cysts 9 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 4 5.00 Very Low Very Low Very Low
Retinal Diseases 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found a substantial increase in HIF-1 protein during hypoxia, but this does not mean that HIF-1 alone regulated gene expression.
Neg (not) Regulation (regulated) of Gene_expression (expression) of HIF-1 associated with hypoxia
1) Confidence 0.32 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2635851 Disease Relevance 1.05 Pain Relevance 0.04
In addition, it has been reported that NO can modulate the level of HIF-1?
Regulation (modulate) of Gene_expression (level) of HIF-1
2) Confidence 0.29 Published 2007 Journal The Open Biochemistry Journal Section Body Doc Link PMC2570544 Disease Relevance 0.77 Pain Relevance 0.09

General Comments

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