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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Map3k1, Bcl2) mitochondrion (Bcl2) aging (Bcl2)
cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2) intracellular (Bcl2)
Map3k1 (Rattus norvegicus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 1 80.64 Quite High
cva 1 43.60 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 31 99.62 Very High Very High Very High
Stress 19 93.80 High High
Hyperglycemia 2 86.40 High High
Diabetes Mellitus 54 84.80 Quite High
Diabetic Cardiomyopathies 2 83.52 Quite High
Injury 4 51.04 Quite High
Coronary Heart Disease 3 44.36 Quite Low
Cv General 3 Under Development 1 43.60 Quite Low
Hypertension 3 42.72 Quite Low
Peripheral Arterial Disease 2 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Yoon et al. [39] postulated that H2O2 induces an increase in apoptosis signal regulating kinase-1 which cause down regulation of antiapoptotic Bcl-2, disruption of the mitochondrial membrane potential and activation of caspase cascade [40].
kinase-1 Positive_regulation (cause) of Regulation (regulation) of Bcl-2 associated with apoptosis
1) Confidence 0.01 Published 2008 Journal The Open Cardiovascular Medicine Journal Section Body Doc Link PMC2570581 Disease Relevance 1.10 Pain Relevance 0.04

General Comments

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