INT250047

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gria2) endoplasmic reticulum (Gria2) plasma membrane (Gria2)
protein complex (Gria2)
Anatomy Link Frequency
plasma 2
Gria2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 33 100.00 Very High Very High Very High
Spinal sensitization 1 99.76 Very High Very High Very High
central sensitization 9 92.68 High High
Anterior cingulate cortex 64 90.48 High High
Pyramidal cell 12 90.16 High High
nMDA receptor 9 86.32 High High
Kinase C 18 56.00 Quite High
IPN 20 50.00 Quite Low
Glutamate receptor 18 46.00 Quite Low
nMDA receptor antagonist 2 43.32 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 32 96.72 Very High Very High Very High
Inflammatory Pain 20 50.00 Quite Low
Nociception 28 37.60 Quite Low
Pain 42 34.84 Quite Low
Hyperalgesia 5 32.96 Quite Low
INFLAMMATION 17 32.44 Quite Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The translocation of AMPA receptors from the cytosol to the plasma membrane also requires the involvement of Stargazin.
Positive_regulation (requires) of Localization (translocation) of AMPA in plasma
1) Confidence 0.41 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0 Pain Relevance 0.17
The enhanced amplitude of EPSCs by octopamine in Ap oa1 mice may be due to increased function of postsynaptic AMPA receptor or presynaptic glutamate release.
Positive_regulation (increased) of Localization (release) of AMPA associated with glutamate
2) Confidence 0.09 Published 2008 Journal Mol Pain Section Body Doc Link PMC2570662 Disease Relevance 0.44 Pain Relevance 0.26

General Comments

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