INT250062

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin2b) embryo development (Grin2b)
Grin2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 34 94.84 High High
amygdala 16 52.88 Quite High
Hippocampus 20 52.36 Quite High
nMDA receptor 8 50.00 Quite Low
long-term potentiation 148 48.88 Quite Low
imagery 12 25.04 Quite Low
Pyramidal cell 6 5.00 Very Low Very Low Very Low
isoflurane 6 5.00 Very Low Very Low Very Low
Action potential 6 5.00 Very Low Very Low Very Low
Anterior cingulate cortex 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 94 93.72 High High
Pain 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although NVP-AAM077 could act at NR2B as well, it is unlikely that the NVP-AAM077 effect was mediated by NR2B-NMDARs, because similar treatment with the selective NR2B-NMDAR antagonist ifenprodil (0.2 ?
Positive_regulation (at) of Transcription (act) of NR2B associated with antagonist
1) Confidence 0.39 Published 2008 Journal Mol Brain Section Body Doc Link PMC2570668 Disease Relevance 0.23 Pain Relevance 0.17
Although NVP-AAM077 could act at NR2B as well, it is unlikely that the NVP-AAM077 effect was mediated by NR2B-NMDARs, because similar treatment with the selective NR2B-NMDAR antagonist ifenprodil (0.2 ?
Positive_regulation (well) of Transcription (act) of NR2B associated with antagonist
2) Confidence 0.39 Published 2008 Journal Mol Brain Section Body Doc Link PMC2570668 Disease Relevance 0.24 Pain Relevance 0.17

General Comments

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