INT250095

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.67
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OXT) extracellular space (OXT) extracellular region (OXT)
response to stress (OXT) cytoplasm (OXT)
Anatomy Link Frequency
plasma 4
neurons 2
OXT (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 24 96.88 Very High Very High Very High
Neuropeptide 108 96.20 Very High Very High Very High
isoflurane 12 82.00 Quite High
depression 6 72.80 Quite High
anesthesia 12 58.72 Quite High
agonist 24 37.36 Quite Low
Intracerebroventricular 12 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
Rostral ventrolateral medulla 6 5.00 Very Low Very Low Very Low
Nicotine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 6 94.84 High High
Premature Birth 12 93.12 High High
Pre-term Labor 12 89.24 High High
Depression 6 72.80 Quite High
Pressure Volume 2 Under Development 12 60.56 Quite High
Fetal Weight 6 48.96 Quite Low
Stress 6 23.48 Low Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Natriuresis 6 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The significant enhancement of activity of fetal AVP and OT neurons suggests that central cholinergic mechanisms is functional in the control of the hypothalamic neuropeptide systems.
Positive_regulation (enhancement) of Gene_expression (neurons) of OT in neurons associated with neuropeptide
1) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.12 Pain Relevance 0.08
Therefore, those environmental and maternal factors could also subsequently produce a higher level of OT in utero according to the new finding in the present study.
Positive_regulation (level) of Gene_expression (produce) of OT
2) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.42 Pain Relevance 0.05
AVP and OT recoveries average 70% in our laboratory.
Positive_regulation (recoveries) of Gene_expression (recoveries) of OT
3) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.05 Pain Relevance 0.13
The i.c.v. carbachol significantly increased fetal plasma AVP and OT levels (AVP: F28,6 = 43.23; OT: F28,6 = 35.40, respectively, both P < 0.01, the baseline period vs the period after i.c.v. injection) (Figure 1 and 2).
Positive_regulation (fetal) of Gene_expression (levels) of OT in plasma
4) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0 Pain Relevance 0
The i.c.v. carbachol significantly increased fetal plasma AVP and OT levels (AVP: F28,6 = 43.23; OT: F28,6 = 35.40, respectively, both P < 0.01, the baseline period vs the period after i.c.v. injection) (Figure 1 and 2).
Positive_regulation (increased) of Gene_expression (levels) of OT in plasma
5) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0 Pain Relevance 0
Samples for AVP and OT extraction were acidified with 1N HCl and extracted.
Positive_regulation (Samples) of Gene_expression (extraction) of OT
6) Confidence 0.09 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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