INT250243

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.78 Pain Relevance 0.06

plasma membrane (FCGR3A, SLC1A2) extracellular region (FCGR3A) transmembrane transport (SLC1A2)

Anatomy Link Frequency plasma 2 FCGR3A (Homo sapiens) SLC1A2 (Homo sapiens)

Pain Link Frequency Relevance Heat Glutamate 54 72.56 addiction 1 9.20 Central nervous system 21 5.00 Spinal cord 15 5.00 Multiple sclerosis 8 5.00 Inflammation 7 5.00 Glutamate receptor 4 5.00 excitatory amino acid 2 5.00 Demyelination 2 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Neuromyelitis Optica 87 100.00 Demyelinating Disease 15 5.00 INFLAMMATION 8 5.00 Toxicity 5 5.00 Targeted Disruption 3 5.00 Neurodegenerative Disease 3 5.00 Autoimmune Disease 3 5.00 Pressure And Volume Under Development 2 5.00 Necrosis 1 5.00 Disease Progression 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We excluded the possibility that NMO serum might contain EAAT2-specific IgG in addition to AQP4 IgG, by testing the effect of NMO serum on plasma membrane expression of EAAT2 in HEK-293 cells transfected with AQP5-GFP (Fig. 4 C).

IgG Regulation (effect) of Gene_expression (expression) of EAAT2 in plasma associated with neuromyelitis optica

1) Confidence 0.00 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571922 Disease Relevance 0.78 Pain Relevance 0.06

General Comments

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