INT250252

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC1A2, GOPC) Golgi apparatus (GOPC) cytoplasm (GOPC)
transmembrane transport (SLC1A2)
Anatomy Link Frequency
astrocytes 1
SLC1A2 (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 15 99.72 Very High Very High Very High
Central nervous system 21 98.96 Very High Very High Very High
Glutamate 54 95.00 High High
Multiple sclerosis 8 18.16 Low Low
Inflammation 7 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
excitatory amino acid 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 87 87.16 High High
Demyelinating Disease 15 18.16 Low Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our immunohistochemical analysis of nonpathologic human CNS tissue (both cortical and spinal cord) reveal that EAAT2, but not EAAT1, normally colocalizes with AQP4 in gray matter astrocytes (Fig. 5 A) and that EAAT2 is most enriched in spinal cord gray matter (Fig. 5 B, top).
EAAT2 Binding (colocalizes) of Fig in astrocytes associated with central nervous system and spinal cord
1) Confidence 0.05 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571922 Disease Relevance 0.44 Pain Relevance 0.35

General Comments

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