INT25026

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Context Info
Confidence 0.19
First Reported 1983
Last Reported 1998
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.38
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) protein modification process (PLOD1) endoplasmic reticulum (PLOD1)
plasma membrane (FSHR) signal transducer activity (FSHR)
Anatomy Link Frequency
plasma 1
follicle 1
PLOD1 (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 7 98.90 Very High Very High Very High
Clonidine 6 98.56 Very High Very High Very High
tolerance 1 93.16 High High
agonist 1 86.68 High High
Enkephalin 4 83.84 Quite High
Opioid 1 75.00 Quite High
Endogenous opioid 2 62.44 Quite High
Parenteral administration 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Syndrome 5 88.04 High High
Empty Sella Syndrome 1 78.08 Quite High
Stress 1 47.52 Quite Low
Xerostomia 1 31.76 Quite Low
Increased Venous Pressure Under Development 1 30.56 Quite Low
Exanthema 1 29.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of BW 942C on serum growth hormone (GH), luteinizing hormone (LH), prolactin (PR), and follicle-stimulating hormone (FSH) were assessed in three of these volunteers.
LH Regulation (effects) of follicle-stimulating hormone in follicle
1) Confidence 0.19 Published 1987 Journal J Clin Pharmacol Section Abstract Doc Link 3119677 Disease Relevance 0 Pain Relevance 0.21
When naloxone was started 1 h before CRH infusion (5 women), plasma LH and FSH concentrations did not change.
LH Neg (not) Regulation (change) of FSH in plasma associated with narcan
2) Confidence 0.19 Published 1989 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 2493035 Disease Relevance 0 Pain Relevance 0.47
Two girls (Tanner II breast development) had a normal serum estradiol (E2) concentration but high LH and FSH responses to GnRH stimulation.
LH Regulation (responses) of FSH
3) Confidence 0.10 Published 1998 Journal Metab. Clin. Exp. Section Abstract Doc Link 9826209 Disease Relevance 0.38 Pain Relevance 0.08
No changes in FSH, LH, or prolactin were seen after oral clonidine.
LH Neg (No) Regulation (changes) of FSH associated with clonidine
4) Confidence 0.08 Published 1983 Journal Metab. Clin. Exp. Section Abstract Doc Link 6302442 Disease Relevance 0 Pain Relevance 0.39

General Comments

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