INT25027

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Context Info
Confidence 0.25
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.42

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endosome (FSHR) signal transduction (CRH) extracellular space (CRH)
extracellular region (CRH) plasma membrane (FSHR) signal transducer activity (FSHR)
CRH (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 7 99.92 Very High Very High Very High
Opioid 1 75.00 Quite High
Endogenous opioid 2 69.80 Quite High
Disease Link Frequency Relevance Heat
Stress 1 33.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Addition of naloxone to CRH (5 women) reversed the LH and FSH inhibition when naloxone was started 1 h after the start of the CRH infusion.
CRH Negative_regulation (reversed) of Negative_regulation (inhibition) of FSH associated with narcan
1) Confidence 0.25 Published 1989 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 2493035 Disease Relevance 0 Pain Relevance 0.42

General Comments

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