INT250289

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.04
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Adh5) oxidoreductase activity (Adh5) cytoplasm (Adh5)
Adh5 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 10 100.00 Very High Very High Very High
fibrosis 3 67.84 Quite High
anesthesia 5 64.16 Quite High
ketamine 5 57.60 Quite High
antagonist 2 46.40 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiomegaly 3 95.32 Very High Very High Very High
Disease 15 86.64 High High
Hypertension 81 86.00 High High
Pulmonary Disease 15 85.68 High High
Cystic Fibrosis 3 68.40 Quite High
Asthma 6 62.16 Quite High
Rheumatoid Arthritis 27 57.56 Quite High
Sepsis 6 22.48 Low Low
Targeted Disruption 11 19.44 Low Low
Stress 21 14.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, no differences were observed in expression of the Vitamin A┬ľmetabolizing alcohol dehydrogenases ADH1, ADH4, and ADH5 (unpublished data).
Gene_expression (expression) of ADH5 associated with alcohol
1) Confidence 0.38 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571923 Disease Relevance 0.17 Pain Relevance 0.05
Measurement of S-nitrosoglutathione reductase activity
Gene_expression (activity) of S-nitrosoglutathione reductase
2) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982841 Disease Relevance 0.10 Pain Relevance 0.12
One specific enzyme that regulates S-nitrosothiol catabolism is S-nitrosoglutathione reductase (GSNO-R), a ubiquitously expressed NADH-dependent enzyme [2].
Gene_expression (expressed) of S-nitrosoglutathione reductase
3) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982841 Disease Relevance 0.44 Pain Relevance 0.03
The effects of gender hormones on the expression and activity of the de-nitrosylating enzyme S-nitrosoglutathione reductase (GSNO-R) are undefined.
Gene_expression (expression) of S-nitrosoglutathione reductase
4) Confidence 0.28 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2982841 Disease Relevance 0.34 Pain Relevance 0

General Comments

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