INT250324

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rpsa) structural constituent of ribosome (Rpsa) ribosome (Rpsa)
plasma membrane (Rpsa) nucleus (Rpsa) intracellular (Rpsa)
Anatomy Link Frequency
Th17 cells 1
Rpsa (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 110 88.96 High High
rheumatoid arthritis 67 79.72 Quite High
cytokine 44 63.20 Quite High
Inflammation 19 46.08 Quite Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Arthritis 7 88.96 High High
Arthritis 97 82.24 Quite High
Rheumatoid Arthritis 67 79.72 Quite High
Autoimmune Disease 7 58.00 Quite High
Necrosis 4 50.00 Quite Low
Cancer 4 50.00 Quite Low
Immunization 6 30.56 Quite Low
Disease 40 5.00 Very Low Very Low Very Low
INFLAMMATION 17 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
produced a dose-dependent reduction of p40 upon subsequent stimulation with LPS (Fig. 3).
Negative_regulation (reduction) of p40
1) Confidence 0.21 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571924 Disease Relevance 0.07 Pain Relevance 0.07
The expansion of Th1/Th17 cells was abrogated by blockade of p40 [70].
Negative_regulation (blockade) of p40 in Th17 cells
2) Confidence 0.06 Published 2010 Journal Semin Immunopathol Section Body Doc Link PMC2836464 Disease Relevance 0.82 Pain Relevance 0.41

General Comments

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