INT250326

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Il12a, Rpsa) structural constituent of ribosome (Rpsa) ribosome (Rpsa)
intracellular (Rpsa) cytosol (Rpsa) extracellular space (Il12a)
Anatomy Link Frequency
Th1 cell 1
Il12a (Mus musculus)
Rpsa (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 11 99.00 Very High Very High Very High
rheumatoid arthritis 13 97.92 Very High Very High Very High
Pain 1 89.84 High High
Inflammation 4 84.80 Quite High
chemokine 2 76.52 Quite High
Arthritis 24 51.00 Quite High
addiction 1 37.92 Quite Low
Demyelination 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 13 97.92 Very High Very High Very High
Pain 1 89.84 High High
Pressure And Volume Under Development 3 88.88 High High
INFLAMMATION 5 84.80 Quite High
Disease 10 79.52 Quite High
Autoimmune Disease 1 55.44 Quite High
Arthritis 28 51.00 Quite High
Necrosis 2 50.00 Quite Low
Cancer 2 50.00 Quite Low
Immunization 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-23 is a heterodimeric protein composed of a p19 subunit and a p40 subunit, whereas IL-12, an important cytokine for Th1 cell differentiation, is formed when the p40 subunit dimerizes with p35 (8).
p35 Binding (dimerizes) of p40 in Th1 cell associated with cytokine
1) Confidence 0.09 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571924 Disease Relevance 0.93 Pain Relevance 0.59

General Comments

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