INT250354

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Prf1) extracellular region (Prf1) cytoplasmic membrane-bounded vesicle (Prf1)
plasma membrane (Prf1) transmembrane transport (Prf1)
Anatomy Link Frequency
pore 2
Prf1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 18 93.40 High High
Retina Disease 2 88.48 High High
Disease 6 64.92 Quite High
Targeted Disruption 16 59.48 Quite High
Ocular Toxicity (including Many Sub-types) 2 16.40 Low Low
Vitelliform Macular Dystrophy 2 6.04 Low Low
Myelodysplastic Syndromes 4 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the rescue experiment alone does not formally prove that dBest1 is the pore-forming subunit of the S2 volume-regulated anion channel (VRAC) because overexpression of an essential regulator or accessory subunit of the channel could have the same effect.
Regulation (regulated) of pore-forming in pore
1) Confidence 0.00 Published 2008 Journal The Journal of General Physiology Section Body Doc Link PMC2571971 Disease Relevance 0.22 Pain Relevance 0
Here, we provide compelling evidence to support the idea that bestrophin-1 is the pore-forming subunit of a cell volume-regulated anion channel (VRAC) in Drosophila S2 cells.
Regulation (regulated) of pore-forming in pore
2) Confidence 0.00 Published 2008 Journal The Journal of General Physiology Section Abstract Doc Link PMC2571971 Disease Relevance 0.09 Pain Relevance 0

General Comments

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