INT250412

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Context Info
Confidence 0.53
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.22
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pyy) extracellular region (Pyy)
Anatomy Link Frequency
bile 3
fat 1
Pyy (Mus musculus)
Pain Link Frequency Relevance Heat
Bile 2 99.20 Very High Very High Very High
Neurotransmitter 3 88.44 High High
tolerance 16 69.36 Quite High
agonist 28 20.56 Low Low
antagonist 43 19.32 Low Low
Neuropeptide 5 9.76 Low Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
qutenza 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Constipation 2 98.10 Very High Very High Very High
Impaired Glucose Tolerance 16 70.00 Quite High
Targeted Disruption 15 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Hyperinsulinism 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Weight Gain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dietary fat, bile salts, carbohydrates, and proteins can stimulate PYY release but to different degrees and with different rates (for review, see Onaga et al. [15]).
Positive_regulation (stimulate) of Localization (release) of PYY in bile associated with bile
1) Confidence 0.53 Published 2008 Journal Nutrition Section Body Doc Link PMC2572019 Disease Relevance 0 Pain Relevance 0.09
We therefore conclude that antidiabetic DPP-IV inhibitors such as vildagliptin may cause constipation, as has been observed clinically (Lauster et al., 2007), but that this is unlikely to involve increased stability of PYY.
Positive_regulation (increased) of Localization (stability) of PYY associated with constipation
2) Confidence 0.49 Published 2010 Journal Cell Metabolism Section Body Doc Link PMC2890049 Disease Relevance 0.22 Pain Relevance 0.06
Dietary fat, bile salts, carbohydrates, and proteins can stimulate PYY release but to different degrees and with different rates (for review, see Onaga et al. [15]).
Positive_regulation (stimulate) of in fat Localization (release) of PYY in bile associated with bile
3) Confidence 0.18 Published 2008 Journal Nutrition Section Body Doc Link PMC2572019 Disease Relevance 0 Pain Relevance 0.09

General Comments

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