INT25048

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Context Info
Confidence 0.32
First Reported 1987
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PLOD1) endoplasmic reticulum (PLOD1)
PLOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 2 97.42 Very High Very High Very High
narcan 3 93.44 High High
Endogenous opioid 1 51.12 Quite High
Disease Link Frequency Relevance Heat
Hypogonadotropic Hypogonadism 3 77.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The repeated administration of GnRH restored the hyporesponsiveness of serum FSH and increased serum testosterone level from less than 1.0 to 1.7 nmol/l, but the impaired LH response to the standard GnRH test was not improved.
Negative_regulation (impaired) of Regulation (response) of LH
1) Confidence 0.32 Published 1987 Journal Acta Endocrinol. Section Abstract Doc Link 3101337 Disease Relevance 0.15 Pain Relevance 0.13
Morphine (9 mg, iv), which had previously been shown to decrease LH and FSH concentrations in ovariectomized monkeys, also significantly decreased LH and FSH concentrations in ADX monkeys of group 1, which did not respond to CRH.
Negative_regulation (decreased) of Regulation (concentrations) of LH associated with morphine
2) Confidence 0.16 Published 1989 Journal Endocrinology Section Abstract Doc Link 2494035 Disease Relevance 0 Pain Relevance 0.19

General Comments

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