INT250508

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.01
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Igf1r) kinase activity (Igf1r)
Anatomy Link Frequency
brain 4
Igf1r (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 52.96 Quite High
Somatostatin 34 5.00 Very Low Very Low Very Low
Central nervous system 14 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 8 96.80 Very High Very High Very High
Death 10 94.44 High High
Lifespan 66 87.76 High High
Targeted Disruption 12 81.84 Quite High
Hyperplasia 2 64.56 Quite High
Pituitary Cancer 2 63.96 Quite High
Cancer 4 59.72 Quite High
INFLAMMATION 4 52.96 Quite High
Aging 30 40.20 Quite Low
Stress 6 38.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We showed that diminishing IGF-1R expression in the brain selectively reduced somatotropic function.
Negative_regulation (diminishing) of Gene_expression (expression) of IGF-1R in brain
1) Confidence 0.42 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2573928 Disease Relevance 1.03 Pain Relevance 0.05
We showed that diminishing IGF-1R expression in the brain selectively reduced somatotropic function.
Negative_regulation (reduced) of Gene_expression (expression) of IGF-1R in brain
2) Confidence 0.42 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2573928 Disease Relevance 0.98 Pain Relevance 0.03

General Comments

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