INT25054

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Context Info
Confidence 0.07
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) extracellular space (Crh) extracellular region (Crh)
plasma membrane (FSHR) signal transducer activity (FSHR) response to stress (Crh)
Anatomy Link Frequency
adrenal glands 1
Crh (Rattus norvegicus)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 4 91.36 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results clearly indicate that in the primate the adrenal glands are not required for the acute CRH inhibitory effect on LH and FSH, and consequently, the decrease in gonadotropins that follows CRH is not mediated by the resultant increase in cortisol release, but, rather, by central mechanisms.
CRH Negative_regulation (effect) of FSH in adrenal glands
1) Confidence 0.07 Published 1989 Journal Endocrinology Section Abstract Doc Link 2494035 Disease Relevance 0 Pain Relevance 0.17
Confirming previous observations, a 5-h iv CRH (rat/human CRH, 100-150 micrograms/h), but not saline, infusion inhibited both LH and FSH secretion.
CRH Negative_regulation (inhibited) of FSH
2) Confidence 0.07 Published 1989 Journal Endocrinology Section Abstract Doc Link 2494035 Disease Relevance 0 Pain Relevance 0

General Comments

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