INT250553

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.36
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SUGT1) mitosis (SUGT1) extracellular space (RS1)
extracellular region (RS1) cell adhesion (RS1)
RS1 (Homo sapiens)
SUGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 17 91.68 High High
Angina 4 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 68 100.00 Very High Very High Very High
Necrosis 47 100.00 Very High Very High Very High
Coronary Artery Disease 75 98.62 Very High Very High Very High
Disease 26 90.72 High High
Cardiovascular Disease 70 89.80 High High
Aseptic Necrosis Of Bone 4 88.80 High High
Myocardial Infarction 38 85.24 High High
Disorder Of Lipid Metabolism 16 70.40 Quite High
Acute Coronary Syndrome 2 53.60 Quite High
Stroke 33 50.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SNP rs2891168 was confirmed as associated with CAD (p < 0.0001) with a G-allele OR of 1.28 (95% CI 1.20-1.36), and SNP rs10811661 was associated with T2D (p = 0.04) with a T-allele OR of 1.19 (95%CI 1.01-1.41).
rs10811661 Binding (associated) of T-allele OR associated with coronary artery disease and diabetes mellitus
1) Confidence 0.00 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2871267 Disease Relevance 1.83 Pain Relevance 0
This result suggests that the rs2269657 G allele might provide a protective effect against AVN as a result of interaction with rs1052717, even though rs2269657 alone was not associated with the disorder.
rs1052717 Binding (interaction) of allele associated with necrosis
2) Confidence 0.00 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2600781 Disease Relevance 0.87 Pain Relevance 0.22
The C allele of the exonic variant rs2304371, which was associated with highest cholesterol values, is the ancestral allele, present in other mammals and located in a highly conserved region.
rs2304371 Binding (associated) of allele
3) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2574036 Disease Relevance 0.66 Pain Relevance 0

General Comments

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