INT250574

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PITX2) transcription factor binding (PITX2)
PITX2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 3 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 15 100.00 Very High Very High Very High
Cardiovascular Disease 70 95.68 Very High Very High Very High
Stroke 33 93.36 High High
Coronary Artery Disease 49 92.68 High High
Obesity 61 66.00 Quite High
Diabetes Mellitus 47 51.24 Quite High
Disorder Of Lipid Metabolism 22 5.00 Very Low Very Low Very Low
Metabolic Syndrome 3 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 3 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several allelic variants conferred disease risk for men and women jointly, including rs1801020 in coagulation factor XII (HR?
Positive_regulation (conferred) of rs1801020 associated with disease
1) Confidence 0.02 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2574036 Disease Relevance 1.50 Pain Relevance 0
Analysis of rs1111875 with fasting glucose under a co-dominant model showed a significant association of the age × rs1111875 (heterozygote vs major homozygote) interaction term with fasting glucose level (Table 4; p = 0.03), suggesting that one copy of the A non-risk allele at rs1111875 increases fasting glucose level with increasing age.
Positive_regulation (increases) of rs1111875
2) Confidence 0.01 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2958899 Disease Relevance 0.29 Pain Relevance 0

General Comments

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