INT250609

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (MCPH1) intracellular (MCPH1) microtubule organizing center (MCPH1)
cytoplasm (MCPH1)
MCPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 3 99.76 Very High Very High Very High
Inflammation 5 85.88 High High
antagonist 12 80.40 Quite High
Serotonin 5 75.24 Quite High
sSRI 1 61.68 Quite High
fluoxetine 3 53.64 Quite High
agonist 2 49.88 Quite Low
gABA 2 37.76 Quite Low
alcohol 1 8.00 Low Low
withdrawal 1 7.36 Low Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 150 100.00 Very High Very High Very High
INFLAMMATION 8 85.88 High High
Hypertrophy 36 67.52 Quite High
Hyperplasia 1 21.16 Low Low
Sleep Disorders 1 13.76 Low Low
Alcohol Addiction 1 8.00 Low Low
Hypoxia 7 5.00 Very Low Very Low Very Low
Overdose 7 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, inhibition of MCT-mediated intestinal absorption may substantially decrease drug bioavailability.
Spec (may) Negative_regulation (decrease) of Negative_regulation (inhibition) of MCT associated with bioavailability
1) Confidence 0.12 Published 2008 Journal AAPS J Section Body Doc Link PMC2574616 Disease Relevance 0 Pain Relevance 0.05
Oral sildenafil, a PDE5 inhibitor, prevented (in a study in which sildenafil was given 1 day after MCT) and reversed (in a study in which sildenafil was given 3 weeks after MCT) the development of PAH in MCT-treated rats, associated with a reduction in the ETA-receptor density in SMCs of pulmonary small arteries (diameter < 100??
Negative_regulation (reversed) of Negative_regulation (development) of MCT associated with pulmonary hypertension
2) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 1.03 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox