INT250658

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (FOS, CCND1) nucleus (FOS, CCND1) cytosol (CCND1)
aging (FOS) nucleolus (FOS) intracellular (CCND1)
Anatomy Link Frequency
node 1
FOS (Homo sapiens)
CCND1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 68 98.72 Very High Very High Very High
Recurrence 2 61.92 Quite High
Apoptosis 47 47.88 Quite Low
Cancer 57 39.68 Quite Low
Stress 1 38.16 Quite Low
Death 5 37.16 Quite Low
Advanced Or Metastatic Breast Cancer 17 35.84 Quite Low
Disease 9 24.56 Low Low
Disease Progression 2 21.84 Low Low
Fatigue 1 12.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B and AP-1 upregulated genes (cyclin D1, urokinase-type plasminogen activator and VEGF) that can dichotomize node-negative ER-positive cases into early and late relapsing subsets, despite adjuvant tamoxifen therapy; they had the greatest ability to predict outcome in younger patients.
AP-1 Positive_regulation (upregulated) of cyclin D1 in node
1) Confidence 0.03 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.60 Pain Relevance 0

General Comments

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