INT250663

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AKT1, MTOR) cytoplasm (AKT1, MTOR) cytosol (AKT1, MTOR)
signal transduction (AKT1, MTOR) kinase activity (AKT1, MTOR) cell differentiation (AKT1)
AKT1 (Homo sapiens)
MTOR (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 9.76 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 57 98.00 Very High Very High Very High
Metastasis 8 94.16 High High
Apoptosis 47 86.24 High High
Breast Cancer 68 80.40 Quite High
Advanced Or Metastatic Breast Cancer 17 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Noninfiltrating Intraductal Carcinoma 6 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The protein mammalian target of rapamycin (mTOR) is activated downstream by phosphorylated Akt.
Phosphorylation (phosphorylated) of Akt Positive_regulation (activated) of mTOR
1) Confidence 0.16 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 1.26 Pain Relevance 0

General Comments

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