INT250664

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PIK3CB, AKT1) cytosol (PIK3CB, AKT1) signal transduction (PIK3CB, AKT1)
nucleus (PIK3CB, AKT1) cell differentiation (AKT1) nucleoplasm (AKT1)
PIK3CB (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 57 97.56 Very High Very High Very High
Apoptosis 47 94.32 High High
Disease 9 79.64 Quite High
Advanced Or Metastatic Breast Cancer 17 69.36 Quite High
Necrosis 4 44.00 Quite Low
Breast Cancer 68 38.64 Quite Low
Metastasis 8 5.00 Very Low Very Low Very Low
Noninfiltrating Intraductal Carcinoma 6 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As a consequence of dysregulation of the cell cycle, PI3K is over-expressed and activates Akt, which-through phosphorylation of NF-?
PI3K Positive_regulation (activates) of Akt
1) Confidence 0.09 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.62 Pain Relevance 0

General Comments

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