INT250665

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (EGFR, PIK3CB) cytoplasm (EGFR, PIK3CB) signal transduction (EGFR, PIK3CB)
extracellular space (EGFR) plasma membrane (EGFR) endosome (EGFR)
EGFR (Homo sapiens)
PIK3CB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
Taxol 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 94 99.24 Very High Very High Very High
Cancer 114 92.00 High High
Disease 18 74.08 Quite High
Advanced Or Metastatic Breast Cancer 34 63.80 Quite High
Breast Cancer 136 52.24 Quite High
Necrosis 8 38.44 Quite Low
Metastasis 16 5.00 Very Low Very Low Very Low
Noninfiltrating Intraductal Carcinoma 12 5.00 Very Low Very Low Very Low
Toxicity 10 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, epidermal growth factor receptor (EGFR), as well as HER2, activate PI3K and enhance cell growth via Akt.
EGFR Positive_regulation (activate) of PI3K
1) Confidence 0.21 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.69 Pain Relevance 0
Also, epidermal growth factor receptor (EGFR), as well as HER2, activate PI3K and enhance cell growth via Akt.
epidermal growth factor receptor Positive_regulation (activate) of PI3K
2) Confidence 0.21 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.70 Pain Relevance 0

General Comments

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