INT250715

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.82
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (ST8SIA4) Golgi apparatus (ST8SIA4)
ST8SIA4 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 12 72.08 Quite High
Inflammation 30 42.64 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
qutenza 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
carrageenan induced 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Advanced Or Metastatic Breast Cancer 17 96.12 Very High Very High Very High
Pulmonary Disease 55 92.48 High High
Malignant Neoplastic Disease 3 80.08 Quite High
Disease Progression 6 78.36 Quite High
Breast Cancer 68 64.16 Quite High
Bronchitis 7 53.04 Quite High
Recurrence 2 52.56 Quite High
Disease 20 52.12 Quite High
Cancer 57 47.76 Quite Low
INFLAMMATION 30 42.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intratumoural administration of a nonreplicating adenoviral vector (Ad5) that contains the human wild-type p53 (Ad5CMV-p53) combined with chemotherapy could increase the efficacy of primary systemic chemotherapy (PST) as measured by pathological complete response (pCR) in the management of patients with locally advanced breast cancer (Table 1).
Positive_regulation (increase) of PST associated with advanced or metastatic breast cancer
1) Confidence 0.09 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.49 Pain Relevance 0
Carbocisteine resets the balance between sialomucins and fucomucins (increasing concentrations of the former and reducing the latter) probably via the intracellular stimulation of sialyl transferase activity (Havez et al 1977).
Positive_regulation (stimulation) of sialyl transferase
2) Confidence 0.02 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650606 Disease Relevance 0.33 Pain Relevance 0.04

General Comments

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