INT250718

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PIK3CB, Birc5) cytosol (PIK3CB, Birc5) nucleus (PIK3CB, Birc5)
nuclear chromosome (Birc5) chromosome segregation (Birc5) intracellular (Birc5)
PIK3CB (Homo sapiens)
Birc5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
Taxol 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 47 99.92 Very High Very High Very High
Breast Cancer 68 90.08 High High
Cancer 57 72.48 Quite High
Disease 9 53.76 Quite High
Advanced Or Metastatic Breast Cancer 17 43.48 Quite Low
Necrosis 4 18.12 Low Low
Metastasis 8 8.48 Low Low
Noninfiltrating Intraductal Carcinoma 6 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further investigations showed that Akt 2 activation protects against docetaxel-induced apoptosis by regulating survivin levels in a PI3K-dependent manner.
PI3K Regulation (regulating) of Gene_expression (levels) of survivin associated with apoptosis
1) Confidence 0.23 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.91 Pain Relevance 0

General Comments

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