INT250730

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Hmgb1, TNF) extracellular region (Hmgb1, TNF) cell morphogenesis (Hmgb1)
intracellular (TNF) extracellular matrix organization (TNF) DNA binding (Hmgb1)
Anatomy Link Frequency
mononuclear cells 2
Hmgb1 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 17 100.00 Very High Very High Very High
cva 42 73.32 Quite High
antagonist 2 17.56 Low Low
Inflammation 12 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
tissue acidosis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 8 98.08 Very High Very High Very High
Injury 56 85.36 High High
Hemorrhagic Shock 46 84.16 Quite High
Disease 2 76.64 Quite High
Pressure Volume 2 Under Development 20 74.88 Quite High
Hemorrhage 53 73.32 Quite High
Death 6 51.76 Quite High
Cv General 3 Under Development 3 48.64 Quite Low
Coagulation Disorder 7 46.76 Quite Low
Cv General 2 Under Development 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, HMGB1 is a cytokine-like molecule that can promote TNF release from mononuclear cells [153].
HMGB1 Positive_regulation (promote) of Localization (release) of TNF in mononuclear cells associated with cytokine
1) Confidence 0.08 Published 2008 Journal Crit Care Section Body Doc Link PMC2575549 Disease Relevance 0.92 Pain Relevance 0.09

General Comments

This test has worked.

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