INT250818

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 5.06
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IFNA2) extracellular region (IFNA2) cell-cell signaling (IFNA2)
Anatomy Link Frequency
plasma 2
arm 2
IFNA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 77.92 Quite High
abdominal pain 4 62.16 Quite High
Inflammation 13 13.12 Low Low
fibrosis 5 12.44 Low Low
corticosteroid 10 5.00 Very Low Very Low Very Low
headache 8 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 14 95.72 Very High Very High Very High
Skin Cancer 28 93.44 High High
Coagulation Disorder 4 90.76 High High
Adult Respiratory Distress Syndrome 42 89.76 High High
Leukocytosis 2 86.04 High High
Capillary Leak Syndrome 2 86.00 High High
Thrombocytopenia 3 84.24 Quite High
Cancer 8 78.92 Quite High
Hypoxia 2 78.68 Quite High
Syndrome 12 75.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, modified release of interferon-alpha was developed to meet patient expectations for less frequent parenteral drug administrations, and to increase sustained virologic response rates by improving patient adherence as well as more sustained drug concentrations with higher plasma concentrations.
Positive_regulation (increase) of Localization (release) of interferon-alpha in plasma
1) Confidence 0.12 Published 2006 Journal International Journal of Nanomedicine Section Body Doc Link PMC2676642 Disease Relevance 0.43 Pain Relevance 0
The treatment arm consisted of an induction phase of pegIFNa-2b given as 6 ?
Positive_regulation (induction) of Localization (phase) of pegIFNa-2b in arm
2) Confidence 0.09 Published 2010 Journal Core Evidence Section Body Doc Link PMC2963921 Disease Relevance 0.61 Pain Relevance 0
Hantavirus causes an increased release of TNF and alpha interferon and increased MHC I antigen presentation [106,107].
Positive_regulation (causes) of Localization (release) of alpha interferon
3) Confidence 0.06 Published 2008 Journal Crit Care Section Body Doc Link PMC2575602 Disease Relevance 2.01 Pain Relevance 0.10
Hantavirus causes an increased release of TNF and alpha interferon and increased MHC I antigen presentation [106,107].
Positive_regulation (increased) of Localization (release) of alpha interferon
4) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2575602 Disease Relevance 2.01 Pain Relevance 0.10

General Comments

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