INT250857

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Mmp3, Ecm1) extracellular region (Mmp3, Ecm1) proteinaceous extracellular matrix (Mmp3, Ecm1)
enzyme binding (Ecm1) protein complex (Mmp3) signal transducer activity (Ecm1)
Mmp3 (Rattus norvegicus)
Ecm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 7 88.00 High High
Pain 5 86.64 High High
Osteoarthritis 38 5.00 Very Low Very Low Very Low
Arthritis 15 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 88.00 High High
Pain 5 86.64 High High
Injury 5 20.04 Low Low
Osteoarthritis 39 5.00 Very Low Very Low Very Low
Arthritis 15 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This indicated that FGF8 may promote degradation of the ECM by production of proteases including MMP-3.
Gene_expression (production) of MMP-3 Spec (may) Positive_regulation (promote) of Protein_catabolism (degradation) of ECM
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575604 Disease Relevance 0.17 Pain Relevance 0.13

General Comments

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