INT250864

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fgf8) plasma membrane (Ptger2) signal transducer activity (Ptger2)
Anatomy Link Frequency
joints 2
Fgf8 (Rattus norvegicus)
Ptger2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Osteoarthritis 38 92.44 High High
Inflammation 7 91.04 High High
metalloproteinase 8 87.16 High High
Arthritis 15 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 39 92.44 High High
INFLAMMATION 8 91.04 High High
Disease Progression 1 74.64 Quite High
Injury 5 45.32 Quite Low
Arthritis 15 14.32 Low Low
Pain 5 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that FGF8 can promote the destruction of articular cartilage by the induction of factors such as MMP-3 and PGE2 in joints.
FGF8 Positive_regulation (promote) of Positive_regulation (induction) of PGE2 in joints
1) Confidence 0.03 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575604 Disease Relevance 0.55 Pain Relevance 0.28

General Comments

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