INT25087

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Context Info
Confidence 0.37
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.28
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dorsal 1
FEA (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 2 99.78 Very High Very High Very High
Raphe 4 98.04 Very High Very High Very High
Serotonin 6 96.40 Very High Very High Very High
Locus ceruleus 2 94.88 High High
antagonist 2 92.00 High High
5HT 2 91.68 High High
agonist 2 86.92 High High
Pain 3 55.92 Quite High
anesthesia 1 16.20 Low Low
Disease Link Frequency Relevance Heat
Epilepsy 2 83.56 Quite High
Stress 20 81.60 Quite High
Pain 1 55.92 Quite High
Hallux Valgus 14 50.00 Quite Low
Congenital Anomalies 4 32.84 Quite Low
Exostoses 1 24.40 Low Low
Body Weight 1 11.60 Low Low
Recurrence 2 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Wound Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that 5-HT mediates suppression of FEA induced by noxious stimulation.
Negative_regulation (suppression) of FEA
1) Confidence 0.37 Published 1989 Journal Epilepsia Section Abstract Doc Link 2498071 Disease Relevance 0.06 Pain Relevance 0.46
Drugs known to depress dorsal raphe unit activity, (+/-)-8-hydroxydipropylaminotetralin (DPAT), imipramine, and fluoxetine prevented suppression of FEA induced by noxious stimulation.
Negative_regulation (suppression) of FEA in dorsal associated with raphe and fluoxetine
2) Confidence 0.37 Published 1989 Journal Epilepsia Section Abstract Doc Link 2498071 Disease Relevance 0.08 Pain Relevance 0.48
In order to improve consistency, we used two different standard FEA software packages: ANSYS WorkbenchTM 10.0 (ANSYS, Inc.
Negative_regulation (packages) of FEA
3) Confidence 0.21 Published 2010 Journal The Open Orthopaedics Journal Section Body Doc Link PMC2905774 Disease Relevance 0.14 Pain Relevance 0.06

General Comments

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